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Overexpression of Nuclear Receptor 5A1 Induces and Maintains an Intermediate State of Conversion between Primed and Naive Pluripotency

Naive and primed human pluripotent stem cells (hPSCs) have provided useful insights into the regulation of pluripotency. However, the molecular mechanisms regulating naive conversion remain elusive. Here, we report intermediate naive conversion induced by overexpressing nuclear receptor 5A1 (NR5A1)...

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Detalles Bibliográficos
Autores principales: Yamauchi, Kaori, Ikeda, Tatsuhiko, Hosokawa, Mihoko, Nakatsuji, Norio, Kawase, Eihachiro, Chuma, Shinichiro, Hasegawa, Kouichi, Suemori, Hirofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066342/
https://www.ncbi.nlm.nih.gov/pubmed/32084386
http://dx.doi.org/10.1016/j.stemcr.2020.01.012