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Overexpression of Nuclear Receptor 5A1 Induces and Maintains an Intermediate State of Conversion between Primed and Naive Pluripotency
Naive and primed human pluripotent stem cells (hPSCs) have provided useful insights into the regulation of pluripotency. However, the molecular mechanisms regulating naive conversion remain elusive. Here, we report intermediate naive conversion induced by overexpressing nuclear receptor 5A1 (NR5A1)...
Autores principales: | Yamauchi, Kaori, Ikeda, Tatsuhiko, Hosokawa, Mihoko, Nakatsuji, Norio, Kawase, Eihachiro, Chuma, Shinichiro, Hasegawa, Kouichi, Suemori, Hirofumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066342/ https://www.ncbi.nlm.nih.gov/pubmed/32084386 http://dx.doi.org/10.1016/j.stemcr.2020.01.012 |
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