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Human Tissue Kallikrein 1 Improves Erectile Dysfunction of Streptozotocin-Induced Diabetic Rats by Inhibition of Excessive Oxidative Stress and Activation of the PI3K/AKT/eNOS Pathway

OBJECTIVE: To investigate the protective effects and mechanisms of human tissue kallikrein 1 (hKLK1) on type 1 diabetes mellitus- (DM-) induced erectile dysfunction in rats. Materials and Methods. The homozygous transgenic rats (TGR) harboring the hKLK1 gene and age-matched wild-type Sprague Dawley...

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Detalles Bibliográficos
Autores principales: Luan, Yang, Cui, Kai, Tang, Zhe, Ruan, Yajun, Liu, Kang, Wang, Tao, Chen, Zhong, Wang, Shaogang, Liu, Jihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066404/
https://www.ncbi.nlm.nih.gov/pubmed/32190176
http://dx.doi.org/10.1155/2020/6834236