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Fertility Outcomes and Sperm-DNA Parameters in Metastatic Melanoma Survivors Receiving Vemurafenib or Dabrafenib Therapy: Case Report

Melanoma is a frequent neoplasm in young adult males in reproductive age, 10% of them degenerating into regional and/or distant metastases (MM). The use of BRAF inhibitors (BRAFi) vemurafenib and dabrafenib is effective in MM patients harboring BRAF V600E/K/D mutations. Despite the increased life ex...

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Detalles Bibliográficos
Autores principales: Ghezzi, Marco, Garolla, Andrea, Magagna, Sabina, Šabovich, Iva, Berretta, Massimiliano, Foresta, Carlo, De Toni, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066495/
https://www.ncbi.nlm.nih.gov/pubmed/32211316
http://dx.doi.org/10.3389/fonc.2020.00232