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Connexin43 Hemichannel Targeting With TAT-Gap19 Alleviates Radiation-Induced Endothelial Cell Damage

BACKGROUND: Emerging evidence indicates an excess risk of late occurring cardiovascular diseases, especially atherosclerosis, after thoracic cancer radiotherapy. Ionizing radiation (IR) induces cellular effects which may induce endothelial cell dysfunction, an early marker for atherosclerosis. In ad...

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Detalles Bibliográficos
Autores principales: Ramadan, Raghda, Vromans, Els, Anang, Dornatien Chuo, Goetschalckx, Ines, Hoorelbeke, Delphine, Decrock, Elke, Baatout, Sarah, Leybaert, Luc, Aerts, An
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066501/
https://www.ncbi.nlm.nih.gov/pubmed/32210810
http://dx.doi.org/10.3389/fphar.2020.00212