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Mangiferin Relieves Lipopolysaccharide-Induced Injury by Up-Regulating miR-181a via Targeting PTEN in ATDC5 Cells

BACKGROUND: Mangiferin (MF) was reported to possess anti-inflammatory activity. This investigation tried to probe into the underlying mechanism of MF in osteoarthritis. METHODS: ATDC5 cells were pretreated with series concentrations of MF (0.1, 1, 5, 10, 15, 20 μM) for 2 h and then were exposed to l...

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Detalles Bibliográficos
Autores principales: Ma, Yunfei, Liu, Ying, Ma, Yunyan, Jiang, Nan, Wang, Lei, Wang, Bowei, Niu, Wanting, Hu, Yanjun, Lin, Qingrong, Yu, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066527/
https://www.ncbi.nlm.nih.gov/pubmed/32210798
http://dx.doi.org/10.3389/fphar.2020.00137