Molecular Modeling Study of Uncharged Oximes Compared to HI-6 and 2-PAM Inside Human AChE Sarin and VX Conjugates

[Image: see text] The deleterious effects of nerve agents over the enzymes acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) turned these compounds into the most dangerous chemical weapons known. Among the antidotes in use today against these agents, oximes in combination with other drugs...

Descripción completa

Detalles Bibliográficos
Autores principales: Souza, Felipe Rodrigues de, Rodrigues Garcia, Danielle, Cuya, Teobaldo, Pimentel, André Silva, Gonçalves, Arlan da Silva, Alencastro, Ricardo Bicca de, França, Tanos Celmar Costa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066550/
https://www.ncbi.nlm.nih.gov/pubmed/32175496
http://dx.doi.org/10.1021/acsomega.9b03737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066550/
https://www.ncbi.nlm.nih.gov/pubmed/32175496
http://dx.doi.org/10.1021/acsomega.9b03737

Ejemplares similares