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Recent Advances in Understanding Biological GTP Hydrolysis through Molecular Simulation

[Image: see text] GTP hydrolysis is central to biology, being involved in regulating a wide range of cellular processes. However, the mechanisms by which GTPases hydrolyze this critical reaction remain controversial, with multiple mechanistic possibilities having been proposed based on analysis of e...

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Detalles Bibliográficos
Autores principales: Calixto, Ana Rita, Moreira, Cátia, Kamerlin, Shina Caroline Lynn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066566/
https://www.ncbi.nlm.nih.gov/pubmed/32175485
http://dx.doi.org/10.1021/acsomega.0c00240