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Recent Advances in Understanding Biological GTP Hydrolysis through Molecular Simulation
[Image: see text] GTP hydrolysis is central to biology, being involved in regulating a wide range of cellular processes. However, the mechanisms by which GTPases hydrolyze this critical reaction remain controversial, with multiple mechanistic possibilities having been proposed based on analysis of e...
Autores principales: | Calixto, Ana Rita, Moreira, Cátia, Kamerlin, Shina Caroline Lynn |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066566/ https://www.ncbi.nlm.nih.gov/pubmed/32175485 http://dx.doi.org/10.1021/acsomega.0c00240 |
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