Reversal of ABCB1-related multidrug resistance by ERK5-IN-1

BACKGROUND: Inhibition of ABC transporters is considered the most effective way to circumvent multidrug resistance (MDR). In the present study, we evaluated the MDR modulatory potential of ERK5-IN-1, a potent extracelluar signal regulated kinase 5 (ERK5) inhibitor. METHODS: The cytotoxicity and MDR...

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Detalles Bibliográficos
Autores principales: Wang, Fang, Li, Delan, Zheng, ZongHeng, Kin Wah To, Kenneth, Chen, Zhen, Zhong, Mengjun, Su, Xiaodong, Chen, Likun, Fu, Liwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066765/
https://www.ncbi.nlm.nih.gov/pubmed/32164732
http://dx.doi.org/10.1186/s13046-020-1537-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066765/
https://www.ncbi.nlm.nih.gov/pubmed/32164732
http://dx.doi.org/10.1186/s13046-020-1537-9

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