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Histone deacetylase inhibitors induce expression of chromosomally tagged variant-specific surface protein genes in Giardia lamblia

OBJECTIVE: RNA interference and miRNA mediated mechanisms have been proposed to explain the expression of a specific variant of VSP at a time on the surface of Giardia lamblia. Recently, epigenetic mechanisms involving histone acetylations have been proposed to explain the process of vsp gene switch...

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Detalles Bibliográficos
Autores principales: Orozco, Daniel Roberto, Garlapati, Srinivas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066823/
https://www.ncbi.nlm.nih.gov/pubmed/32164775
http://dx.doi.org/10.1186/s13104-020-04995-6