Sialidase NEU1 suppresses progression of human bladder cancer cells by inhibiting fibronectin-integrin α5β1 interaction and Akt signaling pathway

BACKGROUND: Sialic acids are widely distributed in animal tissues, and aberrantly expressed in a variety of cancer types. High expression of sialic acid contributes to tumor aggressiveness by promoting cell proliferation, migration, angiogenesis, and metastasis. Sialidases are responsible for remova...

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Detalles Bibliográficos
Autores principales: Zhou, Xiaoman, Zhai, Yanhong, Liu, Changmei, Yang, Ganglong, Guo, Jia, Li, Guang, Sun, Chengwen, Qi, Xiaowei, Li, Xiang, Guan, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066847/
https://www.ncbi.nlm.nih.gov/pubmed/32164705
http://dx.doi.org/10.1186/s12964-019-0500-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066847/
https://www.ncbi.nlm.nih.gov/pubmed/32164705
http://dx.doi.org/10.1186/s12964-019-0500-x

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