Advanced maternal age alters expression of maternal effect genes that are essential for human oocyte quality

To investigate the effects of maternal age on the quality of oocytes, we used single-cell RNA sequencing to detect global gene transcriptome and identify key genes affected by advanced age in human mature oocytes. We isolated mRNA from mature oocytes obtained from IVF or ICSI patients (three oocytes...

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Detalles Bibliográficos
Autores principales: Zhang, Jing-Jing, Liu, Xiaoyan, Chen, Li, Zhang, Shouxin, Zhang, Xia, Hao, Cuifang, Miao, Yi-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066876/
https://www.ncbi.nlm.nih.gov/pubmed/32096767
http://dx.doi.org/10.18632/aging.102864

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066876/
https://www.ncbi.nlm.nih.gov/pubmed/32096767
http://dx.doi.org/10.18632/aging.102864

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