LINC00623/miR-101/HRAS axis modulates IL-1β-mediated ECM degradation, apoptosis and senescence of osteoarthritis chondrocytes

Chondrocyte apoptosis and extracellular matrix (ECM) degeneration have been implicated in the pathogenesis of osteoarthritis (OA). Based on previously reported microarray analysis, HRAS (Harvey rat sarcoma viral oncogene homolog), a member of the RAS protein family, was chosen as a potential regulat...

Descripción completa

Detalles Bibliográficos
Autores principales: Lü, Guohua, Li, Lei, Wang, Bing, Kuang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066905/
https://www.ncbi.nlm.nih.gov/pubmed/32062610
http://dx.doi.org/10.18632/aging.102801

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066905/
https://www.ncbi.nlm.nih.gov/pubmed/32062610
http://dx.doi.org/10.18632/aging.102801

Ejemplares similares