SOCS1 blocks G1-S transition in hepatocellular carcinoma by reducing the stability of the CyclinD1/CDK4 complex in the nucleus

Inhibitors of the CDK family of proteins have been approved for the treatment of a variety of tumours; however, the development of new drugs administered in combination with CDK inhibitors is expected to improve the therapeutic effect. We identified the function of suppressor of cytokine signalling...

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Detalles Bibliográficos
Autores principales: Ding, Jun, Xu, Kangdi, Sun, Suwan, Qian, Chao, Yin, Shengyong, Xie, Haiyang, Zhou, Lin, Zheng, Shusen, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066915/
https://www.ncbi.nlm.nih.gov/pubmed/32096766
http://dx.doi.org/10.18632/aging.102865

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066915/
https://www.ncbi.nlm.nih.gov/pubmed/32096766
http://dx.doi.org/10.18632/aging.102865

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