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SOCS1 blocks G1-S transition in hepatocellular carcinoma by reducing the stability of the CyclinD1/CDK4 complex in the nucleus

Inhibitors of the CDK family of proteins have been approved for the treatment of a variety of tumours; however, the development of new drugs administered in combination with CDK inhibitors is expected to improve the therapeutic effect. We identified the function of suppressor of cytokine signalling...

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Detalles Bibliográficos
Autores principales:	Ding, Jun, Xu, Kangdi, Sun, Suwan, Qian, Chao, Yin, Shengyong, Xie, Haiyang, Zhou, Lin, Zheng, Shusen, Zhang, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066915/ https://www.ncbi.nlm.nih.gov/pubmed/32096766 http://dx.doi.org/10.18632/aging.102865

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