Orai, STIM, and PMCA contribute to reduced calcium signal generation in CD8(+) T cells of elderly mice

Ca(2+) is a crucial second messenger for proper T cell function. Considering the relevance of Ca(2+) signals for T cell functionality it is surprising that no mechanistic insights into T cell Ca(2+) signals from elderly individuals are reported. The main Ca(2+) entry mechanism in T cells are STIM-ac...

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Detalles Bibliográficos
Autores principales: Angenendt, Adrian, Steiner, Romy, Knörck, Arne, Schwär, Gertrud, Konrad, Maik, Krause, Elmar, Lis, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066920/
https://www.ncbi.nlm.nih.gov/pubmed/32062611
http://dx.doi.org/10.18632/aging.102809

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066920/
https://www.ncbi.nlm.nih.gov/pubmed/32062611
http://dx.doi.org/10.18632/aging.102809

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