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Orai, STIM, and PMCA contribute to reduced calcium signal generation in CD8(+) T cells of elderly mice
Ca(2+) is a crucial second messenger for proper T cell function. Considering the relevance of Ca(2+) signals for T cell functionality it is surprising that no mechanistic insights into T cell Ca(2+) signals from elderly individuals are reported. The main Ca(2+) entry mechanism in T cells are STIM-ac...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066920/ https://www.ncbi.nlm.nih.gov/pubmed/32062611 http://dx.doi.org/10.18632/aging.102809 |