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Adaptive selection in the evolution of programmed cell death-1 and its ligands in vertebrates

Programmed cell death-1 (PD-1) and its ligands, particularly PD-L1 and PD-L2, are the most important proteins responsible for signaling T-cell inhibition and arbitrating immune homeostasis and tolerance mechanisms. However, the adaptive evolution of these genes is poorly understood. In this study, w...

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Detalles Bibliográficos
Autores principales: Ahmad, Hafiz Ishfaq, Zhou, Jiabin, Ahmad, Muhammad Jamil, Afzal, Gulnaz, Jiang, Haiying, Zhang, Xiujuan, Elokil, Abdelmotaleb A., Khan, Musarrat Abbas, Li, Linmiao, Li, Huiming, Ping, Liu, Chen, Jinping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066927/
https://www.ncbi.nlm.nih.gov/pubmed/32045365
http://dx.doi.org/10.18632/aging.102827