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Human papillomavirus type 18 E5 oncoprotein cooperates with E6 and E7 in promoting cell viability and invasion and in modulating the cellular redox state

BACKGROUND: High-risk human papillomaviruses (HR-HPVs) are the etiological agents of cervical cancer. Among them, types 16 and 18 are the most prevalent worldwide. The HPV genome encodes three oncoproteins (E5, E6, and E7) that possess a high transformation potential in culture cells when transduced...

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Detalles Bibliográficos
Autores principales: Hochmann, Jimena, Parietti, Felipe, Martínez, Jennyfer, Lopez, Ana C, Carreño, Mara, Quijano, Celia, Boccardo, Enrique, Sichero, Laura, Möller, Matías N, Mirazo, Santiago, Arbiza, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066992/
https://www.ncbi.nlm.nih.gov/pubmed/32187327
http://dx.doi.org/10.1590/0074-02760190405