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Dihydroartemisinin Ameliorates Learning and Memory in Alzheimer’s Disease Through Promoting Autophagosome-Lysosome Fusion and Autolysosomal Degradation for Aβ Clearance

Dihydroartemisinin (DHA) is an active metabolite of sesquiterpene trioxane lactone extracted from Artemisia annua, which is used to treat malaria worldwide. DHA can activate autophagy, which is the main mechanism to remove the damaged cell components and recover the harmful or useless substances fro...

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Detalles Bibliográficos
Autores principales: Zhao, Yueyang, Long, Zhimin, Ding, Ya, Jiang, Tingting, Liu, Jiajun, Li, Yimin, Liu, Yuanjie, Peng, Xuehua, Wang, Kejian, Feng, Min, He, Guiqiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067048/
https://www.ncbi.nlm.nih.gov/pubmed/32210783
http://dx.doi.org/10.3389/fnagi.2020.00047