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Endosomal Wnt signaling proteins control microtubule nucleation in dendrites

Dendrite microtubules are polarized with minus-end-out orientation in Drosophila neurons. Nucleation sites concentrate at dendrite branch points, but how they localize is not known. Using Drosophila, we found that canonical Wnt signaling proteins regulate localization of the core nucleation protein...

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Detalles Bibliográficos
Autores principales: Weiner, Alexis T., Seebold, Dylan Y., Torres-Gutierrez, Pedro, Folker, Christin, Swope, Rachel D., Kothe, Gregory O., Stoltz, Jessica G., Zalenski, Madeleine K., Kozlowski, Christopher, Barbera, Dylan J., Patel, Mit A., Thyagarajan, Pankajam, Shorey, Matthew, Nye, Derek M. R., Keegan, Matthew, Behari, Kana, Song, Song, Axelrod, Jeffrey D., Rolls, Melissa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067398/
https://www.ncbi.nlm.nih.gov/pubmed/32163403
http://dx.doi.org/10.1371/journal.pbio.3000647