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Effects of intestinal flora on the pharmacokinetics and pharmacodynamics of aspirin in high-altitude hypoxia

Since hypobaric hypoxia significantly affects metabolic characteristics of intestinal flora, which plays an important role in the biotransformation of aspirin, high altitudes may influence the pharmacokinetics and therapeutic effects of aspirin in the intestines. In the present study, to test altera...

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Detalles Bibliográficos
Autores principales: Sun, Yuemei, Zhang, Juanhong, Zhao, Anpeng, Li, Wenbin, Feng, Qiangsheng, Wang, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067402/
https://www.ncbi.nlm.nih.gov/pubmed/32163488
http://dx.doi.org/10.1371/journal.pone.0230197