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Effects of intestinal flora on the pharmacokinetics and pharmacodynamics of aspirin in high-altitude hypoxia
Since hypobaric hypoxia significantly affects metabolic characteristics of intestinal flora, which plays an important role in the biotransformation of aspirin, high altitudes may influence the pharmacokinetics and therapeutic effects of aspirin in the intestines. In the present study, to test altera...
Autores principales: | Sun, Yuemei, Zhang, Juanhong, Zhao, Anpeng, Li, Wenbin, Feng, Qiangsheng, Wang, Rong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067402/ https://www.ncbi.nlm.nih.gov/pubmed/32163488 http://dx.doi.org/10.1371/journal.pone.0230197 |
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