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Transient pentameric IgM fulfill biological function—Effect of expression host and transfection on IgM properties

Recombinant production of IgM antibodies poses a special challenge due to the complex structure of the proteins and their not yet fully elucidated interactions with the immune effector proteins, especially the complement system. In this study, we present transient expression of IgM antibodies (IgM61...

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Detalles Bibliográficos
Autores principales: Hennicke, Julia, Schwaigerlehner, Linda, Grünwald-Gruber, Clemens, Bally, Isabelle, Ling, Wai Li, Thielens, Nicole, Reiser, Jean-Baptiste, Kunert, Renate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067452/
https://www.ncbi.nlm.nih.gov/pubmed/32163462
http://dx.doi.org/10.1371/journal.pone.0229992