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A comparison of Chikungunya virus infection, progression, and cytokine profiles in human PMA-differentiated U937 and murine RAW264.7 monocyte derived macrophages

Chikungunya virus (CHIKV) is a mosquito-borne alphavirus that causes rash, fever and severe polyarthritis that can last for years in humans. Murine models display inflammation and macrophage infiltration only in the adjacent tissues at the site of inoculation, showing no signs of systemic polyarthri...

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Detalles Bibliográficos
Autores principales: Guerrero-Arguero, Israel, Høj, Taalin R., Tass, E. Shannon, Berges, Bradford K., Robison, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067478/
https://www.ncbi.nlm.nih.gov/pubmed/32163514
http://dx.doi.org/10.1371/journal.pone.0230328