Bayesian network analysis incorporating genetic anchors complements conventional Mendelian randomization approaches for exploratory analysis of causal relationships in complex data

Mendelian randomization (MR) implemented through instrumental variables analysis is an increasingly popular causal inference tool used in genetic epidemiology. But it can have limitations for evaluating simultaneous causal relationships in complex data sets that include, for example, multiple geneti...

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Detalles Bibliográficos
Autores principales: Howey, Richard, Shin, So-Youn, Relton, Caroline, Davey Smith, George, Cordell, Heather J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067488/
https://www.ncbi.nlm.nih.gov/pubmed/32119656
http://dx.doi.org/10.1371/journal.pgen.1008198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067488/
https://www.ncbi.nlm.nih.gov/pubmed/32119656
http://dx.doi.org/10.1371/journal.pgen.1008198

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