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Low utilization of glucose in the liver causes diet-induced hypercholesterolemia in exogenously hypercholesterolemic rats

Exogenously hypercholesterolemic (ExHC) rats develop diet-induced hypercholesterolemia (DIHC) when fed with dietary cholesterol. Previously, we reported that, under the high-sucrose-diet-feeding condition, a loss-of-function mutation in Smek2 results in low activity of fatty acid synthase (FAS) foll...

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Detalles Bibliográficos
Autores principales: Tanaka, Yasutake, Ono, Masahiro, Miyago, Motonori, Suzuki, Takahisa, Miyazaki, Yurika, Kawano, Michio, Asahina, Makoto, Shirouchi, Bungo, Imaizumi, Katsumi, Sato, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067558/
https://www.ncbi.nlm.nih.gov/pubmed/32163433
http://dx.doi.org/10.1371/journal.pone.0229669