Cargando…

Metabolic and non-metabolic liver zonation is established non-synchronously and requires sinusoidal Wnts

The distribution of complementary metabolic functions in hepatocytes along a portocentral axis is called liver zonation. Endothelial secreted Wnt ligands maintain metabolic zonation in the adult murine liver but whether those ligands are necessary to initiate zonation in the immature liver has been...

Descripción completa

Detalles Bibliográficos
Autores principales: Ma, Ruihua, Martínez-Ramírez, Angelica S, Borders, Thomas L, Gao, Fanding, Sosa-Pineda, Beatriz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067564/
https://www.ncbi.nlm.nih.gov/pubmed/32154783
http://dx.doi.org/10.7554/eLife.46206