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Metabolic and non-metabolic liver zonation is established non-synchronously and requires sinusoidal Wnts
The distribution of complementary metabolic functions in hepatocytes along a portocentral axis is called liver zonation. Endothelial secreted Wnt ligands maintain metabolic zonation in the adult murine liver but whether those ligands are necessary to initiate zonation in the immature liver has been...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067564/ https://www.ncbi.nlm.nih.gov/pubmed/32154783 http://dx.doi.org/10.7554/eLife.46206 |