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Comparative Molecular Biology Approaches for the Production of Poliovirus Virus-Like Particles Using Pichia pastoris

For enteroviruses such as poliovirus (PV), empty capsids, which are antigenically indistinguishable from mature virions, are produced naturally during viral infection. The production of such capsids recombinantly, in heterologous systems such as yeast, have great potential as virus-like particle (VL...

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Detalles Bibliográficos
Autores principales: Sherry, Lee, Grehan, Keith, Snowden, Joseph S., Knight, Michael L., Adeyemi, Oluwapelumi O., Rowlands, David J., Stonehouse, Nicola J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067596/
https://www.ncbi.nlm.nih.gov/pubmed/32161150
http://dx.doi.org/10.1128/mSphere.00838-19