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Nur77-activated lncRNA WFDC21P attenuates hepatocarcinogenesis via modulating glycolysis

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related mortality worldwide. Orphan nuclear receptor Nur77, which is low expressed in HCC, functions as a tumor suppressor to suppress HCC. However, the detailed mechanism is still not well understood. Here, we demonstrate that Nu...

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Detalles Bibliográficos
Autores principales: Guan, Yun-feng, Huang, Qiao-ling, Ai, Yuan-li, Chen, Qi-tao, Zhao, Wen-xiu, Wang, Xiao-min, Wu, Qiao, Chen, Hang-zi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067692/
https://www.ncbi.nlm.nih.gov/pubmed/31959898
http://dx.doi.org/10.1038/s41388-020-1158-y