Prediction of Clearance in Children from Adults Following Drug–Drug Interaction Studies: Application of Age-Dependent Exponent Model

BACKGROUND AND OBJECTIVE: Pharmacokinetic drug–drug interaction (DDI) studies are conducted in adult subjects during drug development but there are limited studies that have characterized pharmacokinetic DDI studies in children. The objective of this study was to evaluate if the DDI clearance values...

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Detalles Bibliográficos
Autor principal: Mahmood, Iftekhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067713/
https://www.ncbi.nlm.nih.gov/pubmed/32056156
http://dx.doi.org/10.1007/s40268-020-00295-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067713/
https://www.ncbi.nlm.nih.gov/pubmed/32056156
http://dx.doi.org/10.1007/s40268-020-00295-3

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