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NDRG2 Protects the Brain from Excitotoxicity by Facilitating Interstitial Glutamate Uptake

Glutamate is a prominent neurotransmitter responsible for excitatory synaptic transmission and is taken up by sodium-dependent excitatory amino acid transporters (EAATs) on astrocytes to maintain synaptic homeostasis. Here, we report that N-myc downstream regulated gene 2 (NDRG2), a known tumor supp...

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Detalles Bibliográficos
Autores principales: Yin, Anqi, Guo, Hang, Tao, Liang, Cai, Guohong, Wang, Yazhou, Yao, Libo, Xiong, Lize, Zhang, Jian, Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067740/
https://www.ncbi.nlm.nih.gov/pubmed/31250377
http://dx.doi.org/10.1007/s12975-019-00708-9