Cargando…

Abundant human anti-Galα3Gal antibodies display broad pathogen reactivity

Antibodies of the IgG class to terminal Galα3Gal (IgG anti-αGal) is abundant in human plasma and are reported to bind most sepsis-causing Gram-negative bacteria. However, these seminal findings, made more than two decades ago, have not been reexamined. Our aim was to assess IgG anti-αGal´s pathogen...

Descripción completa

Detalles Bibliográficos
Autores principales: Bernth Jensen, Jens Magnus, Petersen, Mikkel Steen, Ellerman-Eriksen, Svend, Møller, Bjarne Kuno, Jensenius, Jens Christian, Sørensen, Uffe B. Skov, Thiel, Steffen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067764/
https://www.ncbi.nlm.nih.gov/pubmed/32165720
http://dx.doi.org/10.1038/s41598-020-61632-9