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Prohibitin 2 deficiency impairs cardiac fatty acid oxidation and causes heart failure

Fatty acids are the most major substrate source for adult cardiac energy generation. Prohibitin 2 (PHB2), a highly conserved protein located in mitochondrial inner membrane, plays key roles in cellular energy metabolic homeostasis. However, its functions in regulating cardiac fatty acid metabolism h...

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Detalles Bibliográficos
Autores principales: Wu, Dechao, Jian, Chongshu, Peng, Qi, Hou, Tingting, Wu, Keling, Shang, Bizhi, Zhao, Minglei, Wang, Yanru, Zheng, Wen, Ma, Qi, Li, Chuan-Yun, Cheng, Heping, Wang, Xianhua, Zhao, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067801/
https://www.ncbi.nlm.nih.gov/pubmed/32165613
http://dx.doi.org/10.1038/s41419-020-2374-7