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Prohibitin 2 deficiency impairs cardiac fatty acid oxidation and causes heart failure
Fatty acids are the most major substrate source for adult cardiac energy generation. Prohibitin 2 (PHB2), a highly conserved protein located in mitochondrial inner membrane, plays key roles in cellular energy metabolic homeostasis. However, its functions in regulating cardiac fatty acid metabolism h...
Autores principales: | Wu, Dechao, Jian, Chongshu, Peng, Qi, Hou, Tingting, Wu, Keling, Shang, Bizhi, Zhao, Minglei, Wang, Yanru, Zheng, Wen, Ma, Qi, Li, Chuan-Yun, Cheng, Heping, Wang, Xianhua, Zhao, Ling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067801/ https://www.ncbi.nlm.nih.gov/pubmed/32165613 http://dx.doi.org/10.1038/s41419-020-2374-7 |
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