Accelerated onset of CNS prion disease in mice co-infected with a gastrointestinal helminth pathogen during the preclinical phase

Prion infections in the central nervous system (CNS) can cause extensive neurodegeneration. Systemic inflammation can affect the progression of some neurodegenerative disorders. Therefore, we used the gastrointestinal helminth pathogen Trichuris muris to test the hypothesis that a chronic systemic i...

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Detalles Bibliográficos
Autores principales: Donaldson, David S., Bradford, Barry M., Else, Kathryn J., Mabbott, Neil A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067812/
https://www.ncbi.nlm.nih.gov/pubmed/32165661
http://dx.doi.org/10.1038/s41598-020-61483-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067812/
https://www.ncbi.nlm.nih.gov/pubmed/32165661
http://dx.doi.org/10.1038/s41598-020-61483-4

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