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Novel RvD6 stereoisomer induces corneal nerve regeneration and wound healing post-injury by modulating trigeminal transcriptomic signature

The high-density corneal innervation plays a pivotal role in sustaining the integrity of the ocular surface. We have previously demonstrated that pigment epithelium-derived factor (PEDF) plus docosahexaenoic acid (DHA) promotes corneal nerve regeneration; here, we report the mechanism involved and t...

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Detalles Bibliográficos
Autores principales: Pham, Thang L., Kakazu, Azucena H., He, Jiucheng, Jun, Bokkyoo, Bazan, Nicolas G., Bazan, Haydee E. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067818/
https://www.ncbi.nlm.nih.gov/pubmed/32165657
http://dx.doi.org/10.1038/s41598-020-61390-8