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Perivascular localization of macrophages in the intestinal mucosa is regulated by Nr4a1 and the microbiome

While the ontogeny and recruitment of the intestinal monocyte/macrophage lineage has been studied extensively, their precise localization and function has been overlooked. Here we show by imaging the murine small and large intestines in steady-state that intestinal CX3CR1(+) macrophages form an inte...

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Detalles Bibliográficos
Autores principales: Honda, Masaki, Surewaard, Bas G. J., Watanabe, Mayuki, Hedrick, Catherine C., Lee, Woo-Yong, Brown, Kirsty, McCoy, Kathy D., Kubes, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067862/
https://www.ncbi.nlm.nih.gov/pubmed/32165624
http://dx.doi.org/10.1038/s41467-020-15068-4