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A non-coding genetic variant associated with abdominal aortic aneurysm alters ERG gene regulation

Abdominal aortic aneurysm (AAA) is a major cause of sudden death in the elderly. While AAA has some overlapping genetic and environmental risk factors with atherosclerosis, there are substantial differences, and AAA-specific medication is lacking. A recent meta-analysis of genome-wide association st...

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Detalles Bibliográficos
Autores principales: Marsman, Judith, Gimenez, Gregory, Day, Robert C, Horsfield, Julia A, Jones, Gregory T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068029/
https://www.ncbi.nlm.nih.gov/pubmed/31691800
http://dx.doi.org/10.1093/hmg/ddz256