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Endocannabinoid LTD in Accumbal D1 Neurons Mediates Reward-Seeking Behavior

The nucleus accumbens (NAc) plays a key role in drug-related behavior and natural reward learning. Synaptic plasticity in dopamine D1 and D2 receptor medium spiny neurons (MSNs) of the NAc and the endogenous cannabinoid (eCB) system have been implicated in reward seeking. However, the precise molecu...

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Detalles Bibliográficos
Autores principales: Bilbao, Ainhoa, Neuhofer, Daniela, Sepers, Marja, Wei, Shou-peng, Eisenhardt, Manuela, Hertle, Sarah, Lassalle, Olivier, Ramos-Uriarte, Almudena, Puente, Nagore, Lerner, Raissa, Grandes, Pedro, Lutz, Beat, Manzoni, Olivier J., Spanagel, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068121/
https://www.ncbi.nlm.nih.gov/pubmed/32179475
http://dx.doi.org/10.1016/j.isci.2020.100951