Cargando…
Endocannabinoid LTD in Accumbal D1 Neurons Mediates Reward-Seeking Behavior
The nucleus accumbens (NAc) plays a key role in drug-related behavior and natural reward learning. Synaptic plasticity in dopamine D1 and D2 receptor medium spiny neurons (MSNs) of the NAc and the endogenous cannabinoid (eCB) system have been implicated in reward seeking. However, the precise molecu...
Autores principales: | Bilbao, Ainhoa, Neuhofer, Daniela, Sepers, Marja, Wei, Shou-peng, Eisenhardt, Manuela, Hertle, Sarah, Lassalle, Olivier, Ramos-Uriarte, Almudena, Puente, Nagore, Lerner, Raissa, Grandes, Pedro, Lutz, Beat, Manzoni, Olivier J., Spanagel, Rainer |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068121/ https://www.ncbi.nlm.nih.gov/pubmed/32179475 http://dx.doi.org/10.1016/j.isci.2020.100951 |
Ejemplares similares
-
NMDA Receptors in Accumbal D1 Neurons Influence Chronic Sugar Consumption and Relapse
por: Wei, Shoupeng, et al.
Publicado: (2021) -
Uncoupling of the endocannabinoid signalling complex in a mouse model of fragile X syndrome
por: Jung, Kwang-Mook, et al.
Publicado: (2012) -
Functional and structural deficits at accumbens synapses in a mouse model of Fragile X
por: Neuhofer, Daniela, et al.
Publicado: (2015) -
Female mice are more prone to develop an addictive-like phenotype for sugar consumption
por: Wei, Shoupeng, et al.
Publicado: (2021) -
Cocaine-induced loss of LTD and social impairments are restored by fatty acid amide hydrolase inhibition
por: Alegre-Zurano, Laia, et al.
Publicado: (2023)