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Peroxiredoxin 6 mediates acetaminophen-induced hepatocyte death through JNK activation

Acetaminophen (APAP) is one of the most frequently used drugs; however, its overdose leads to acute liver injury. Recently, studies have reported that the adduction of peroxiredoxin 6 (PRDX6), a member of the PRDX family of antioxidant enzymes, is associated with liver diseases. However, the role of...

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Detalles Bibliográficos
Autores principales: Lee, Dong Hun, Jung, Young Suk, Yun, Jaesuk, Han, Sang Bae, Roh, Yoon Seok, Song, Min Jong, Hong, Jin Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068129/
https://www.ncbi.nlm.nih.gov/pubmed/32171727
http://dx.doi.org/10.1016/j.redox.2020.101496