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Peroxiredoxin 6 mediates acetaminophen-induced hepatocyte death through JNK activation
Acetaminophen (APAP) is one of the most frequently used drugs; however, its overdose leads to acute liver injury. Recently, studies have reported that the adduction of peroxiredoxin 6 (PRDX6), a member of the PRDX family of antioxidant enzymes, is associated with liver diseases. However, the role of...
Autores principales: | Lee, Dong Hun, Jung, Young Suk, Yun, Jaesuk, Han, Sang Bae, Roh, Yoon Seok, Song, Min Jong, Hong, Jin Tae |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068129/ https://www.ncbi.nlm.nih.gov/pubmed/32171727 http://dx.doi.org/10.1016/j.redox.2020.101496 |
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