Patient-Specific Retinal Organoids Recapitulate Disease Features of Late-Onset Retinitis Pigmentosa

Although an increasing number of disease genes have been identified, the exact cellular mechanisms of retinitis pigmentosa (RP) remain largely unclear. Retinal organoids (ROs) derived from the induced pluripotent stem cells (iPSCs) of patients provide a potential but unvalidated platform for deciphe...

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Detalles Bibliográficos
Autores principales: Gao, Mei-Ling, Lei, Xin-Lan, Han, Fang, He, Kai-Wen, Jin, Si-Qian, Zhang, You-You, Jin, Zi-Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068133/
https://www.ncbi.nlm.nih.gov/pubmed/32211407
http://dx.doi.org/10.3389/fcell.2020.00128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068133/
https://www.ncbi.nlm.nih.gov/pubmed/32211407
http://dx.doi.org/10.3389/fcell.2020.00128

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