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Role of Secreted Frizzled-Related Protein 1 and Tumor Necrosis Factor-α (TNF-α) in Bone Loss of Patients with Rheumatoid Arthritis

Bone loss is one of the emerging extra-articular manifestations of rheumatoid arthritis. TNF-α is the main inflammatory cytokine that can directly increase bone resorption. However, its role in bone formation is still unknown, especially related to secreted frizzled-related protein 1 (SFRP-1), an os...

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Detalles Bibliográficos
Autores principales: Ginting, Andi Raga, Hidayat, Rudy, Sumariyono, Sumariyono, Koesnoe, Sukamto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068142/
https://www.ncbi.nlm.nih.gov/pubmed/32190056
http://dx.doi.org/10.1155/2020/9149762