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Generation of Otic Lineages from Integration-Free Human-Induced Pluripotent Stem Cells Reprogrammed by mRNAs

Damage to the sensory hair cells and the spiral ganglion neurons of the cochlea leads to deafness. Induced pluripotent stem cells (iPSCs) are a promising tool to regenerate the cells in the inner ear that have been affected by pathology or have been lost. To facilitate the clinical application of iP...

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Detalles Bibliográficos
Autores principales: Boddy, Sarah L., Romero-Guevara, Ricardo, Ji, Ae-Ri, Unger, Christian, Corns, Laura, Marcotti, Walter, Rivolta, Marcelo N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068143/
https://www.ncbi.nlm.nih.gov/pubmed/32190057
http://dx.doi.org/10.1155/2020/3692937