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Generation of Otic Lineages from Integration-Free Human-Induced Pluripotent Stem Cells Reprogrammed by mRNAs
Damage to the sensory hair cells and the spiral ganglion neurons of the cochlea leads to deafness. Induced pluripotent stem cells (iPSCs) are a promising tool to regenerate the cells in the inner ear that have been affected by pathology or have been lost. To facilitate the clinical application of iP...
Autores principales: | Boddy, Sarah L., Romero-Guevara, Ricardo, Ji, Ae-Ri, Unger, Christian, Corns, Laura, Marcotti, Walter, Rivolta, Marcelo N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068143/ https://www.ncbi.nlm.nih.gov/pubmed/32190057 http://dx.doi.org/10.1155/2020/3692937 |
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