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Changes in the gene mutation profiles of circulating tumor DNA detected using CAPP-Seq in neoadjuvant chemotherapy-treated advanced ovarian cancer

Cancer Personalized Profiling by deep Sequencing (CAPP-Seq) is a novel ultrasensitive next-generation sequencing-based approach that is used to detect circulating tumor DNA (ctDNA). The aim of the present study was to compare the gene mutation profiles and blood tumor mutation burden (bTMB) measured...

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Detalles Bibliográficos
Autores principales: Noguchi, Tomoko, Sakai, Kazuko, Iwahashi, Naoyuki, Matsuda, Kaho, Matsukawa, Hitomi, Yahata, Tamaki, Toujima, Saori, Nishio, Kazuto, Ino, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068231/
https://www.ncbi.nlm.nih.gov/pubmed/32218822
http://dx.doi.org/10.3892/ol.2020.11356